![]() ![]() It may have prognostic value in NAFLD patients indicating a possible cardiovascular disease (CVD) risk increase. We have shown for the first time in the literature that, patients with NAFLD have higher MPV. ![]() In logistic regression analysis (age, gender, NAFLD, body mass index, high-density lipid (HDL) cholesterol, systolic and diastolic blood pressure, triglyceride and fasting plasma glucose were used as covariates) only NAFLD was found to be the independent predictor of MPV (Odds Ratio (OR) 21.98). MPV was positively correlated with AST (r: 0.186, p < 0.042), ALT level (r: 0.279 p 0.002) and the presence of NAFLD (0.492 p < 0.001) but negatively correlated with platelet number (r: -0.26 p 0.004) and creatinine (r: -0.255 p 0.005). NAFLD cases also had lower platelet count and higher MPV (10.43 +/- 1.14 vs. Conditions associated with low MPV results include: Aplastic anemia. Low MPV may mean your bone marrow isn’t producing enough new platelets. Among biochemical variables, fasting plasma glucose and triglyceride were significantly higher in the NAFLD group. What does it mean if your MPV blood test results are low Low results mean that your platelets are smaller than what’s considered normal. NAFLD patients had significantly higher body mass index compared to the control cases. MPV values of the patients with NAFLD and of the patients without fatty liver disease were compared. The aim of the current study was to investigate the MPV in patients who had NAFLD. Non-alcoholic fatty liver disease (NAFLD) is present up to one-third of the general population and the majority of patients with cardio-metabolic risk factors such as abdominal obesity, type 2 diabetes and other components of the metabolic syndrome (MS). ![]() Platelet activation and aggregation are central processes in the pathophysiology of coronary heart disease. Mean platelet volume (MPV) is an indicator of platelet activation. ![]()
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